Increase of vascular resistance due to sclerotic processes in the vessels
Hypertrophy of the heart (increase in the weight of the heart, in men by around 1g / year between the ages of 30 and 80 years, and in women by around. 1.4g / year)(Greenwood in Platt 1976, 83)
Solidification of the heart valve tissue due to increased total collagen
Storage of the aging pigment, lipofuscin (browning of the myocardium)
The vessels
Hardening, decrease in elasticity, and thickening of the walls = physiosclerosis (Bürger 1957, 90)
Calcification of the elastic elements due to storage of calcium and cholesterol