The heart

• Increase of vascular resistance due to sclerotic processes in the vessels
• Hypertrophy of the heart (increase in the weight of the heart, in men by around 1g / year between the ages of 30 and 80 years, and in women by around. 1.4g / year)(Greenwood in Platt 1976, 83)
• Solidification of the heart valve tissue due to increased total collagen
• Storage of the aging pigment, lipofuscin (browning of the myocardium)

The vessels

• Hardening, decrease in elasticity, and thickening of the walls = physiosclerosis (Bürger 1957, 90)
• Calcification of the elastic elements due to storage of calcium and cholesterol
• Veins show fewer changes with age than arteries